Mission
To develop highly selective, well tolerated, and highly effective anti-cancer agents, by selectively targeting altered metabolism in cancer cells. Our immediate goal is to improve the quality of life of patients with Pancreatic Cancer, which is the deadliest cancer worldwide and has limited treatment options.
Vision
To extend and enhance the lives of patients with Gastrointestinal (GI) Cancers.
Learn more about our Clinical Trials:
CPI-613® (devimistat)
Rafael Pharmaceutical’s first-in-class clinical lead compound, CPI-613® (devimistat), targets enzymes that are involved in cancer cell energy metabolism and are located in the mitochondria of cancer cells. CPI-613® is being evaluated in multiple Phase I, I/II, II, and III clinical studies as a single agent, as well as in combination with standard drug therapies, in patients diagnosed with advanced solid tumors or blood cancers.
The U.S. Food and Drug Administration (FDA) has given Rafael approval to initiate pivotal clinical trials in pancreatic cancer and acute myeloid leukemia (AML), and has designated CPI-613® as an orphan drug for the treatment of pancreatic cancer, AML, Myelodysplastic syndromes (MDS), peripheral T-cell lymphoma and Burkitt’s lymphoma. The EMA has granted orphan drug designation to CPI-613® for pancreatic cancer and AML.
World Class Team
Innovation in oncology drug development requires a deep well of scientific, medical and business expertise, and we have assembled an unparalleled team of directors and advisors who are working with Rafael to revolutionize anticancer treatment.
Our Board of Directors and Scientific & Medical Advisory Boards are drawn from the highest echelons of oncology and hematology researchers and physicians, and include seasoned managers from the biotech and pharmaceutical sectors.
In The News
Pancreatic Cancer Action Network
Rafael is a proud sponsor of the Pancreatic Cancer Action Network
Founded in 1999, the Pancreatic Cancer Action Network (PanCAN) is dedicated to fighting one of the world’s toughest cancers. In their urgent mission to save lives, PanCAN attacks pancreatic cancer on all fronts: research, clinical initiatives, patient services, and advocacy.
Rafael Pharmaceuticals has sponsored PanCAN PurpleStride Walks to end Pancreatic Cancer across the country.